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Title: Methods for chromosome-specific staining

Abstract

Methods and compositions for chromosome-specific staining are provided. Compositions comprise heterogenous mixtures of labeled nucleic acid fragments having substantially complementary base sequences to unique sequence regions of the chromosomal DNA for which their associated staining reagent is specific. Methods include methods for making the chromosome-specific staining compositions of the invention, and methods for applying the staining compositions to chromosomes.

Inventors:
 [1];  [2]
  1. (Livermore, CA)
  2. (Walnut Creek, CA)
Publication Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
OSTI Identifier:
870054
Patent Number(s):
US 5447841
Assignee:
Regents Of Univ. Of California (Oakland, CA) LLNL
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
methods; chromosome-specific; staining; compositions; provided; comprise; heterogenous; mixtures; labeled; nucleic; acid; fragments; substantially; complementary; base; sequences; unique; sequence; regions; chromosomal; dna; associated; reagent; specific; applying; chromosomes; compositions comprise; base sequences; chromosomal dna; nucleic acid; base sequence; chromosome-specific staining; complementary base; substantially complementary; staining reagent; acid fragment; /435/436/999/

Citation Formats

Gray, Joe W., and Pinkel, Daniel. Methods for chromosome-specific staining. United States: N. p., 1995. Web.
Gray, Joe W., & Pinkel, Daniel. Methods for chromosome-specific staining. United States.
Gray, Joe W., and Pinkel, Daniel. Sun . "Methods for chromosome-specific staining". United States. https://www.osti.gov/servlets/purl/870054.
@article{osti_870054,
title = {Methods for chromosome-specific staining},
author = {Gray, Joe W. and Pinkel, Daniel},
abstractNote = {Methods and compositions for chromosome-specific staining are provided. Compositions comprise heterogenous mixtures of labeled nucleic acid fragments having substantially complementary base sequences to unique sequence regions of the chromosomal DNA for which their associated staining reagent is specific. Methods include methods for making the chromosome-specific staining compositions of the invention, and methods for applying the staining compositions to chromosomes.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1995},
month = {1}
}

Patent:

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