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Loading and conjugating cavity biostructures

Patent ·
OSTI ID:870039
 [1]
  1. Shoreham, NY
+ Show Author Affiliations
Methods for the preparation and use of a biological delivery system are disclosed. The method of preparation includes the loading of a non-biological material into a biostructure having a load-bearing structure. The method also includes the removal of some of the biostructure's contents and the loading of a non-biological material into the biostructure. The biostructure is biologically compatible with the host, and preferably is derived from the host, the host's species or a related species. The loaded biostructure is used directly, or it can be targeted to specific cells, tissues and/or organs within a host. The targeted biostructure can be used to deliver the non-biological material to a specified tissue, organ or cell within a host for diagnostic, therapeutic or other purposes.
Research Organization:
ASSOC UNIVERSITIES INC
DOE Contract Number:
AC02-76CH00016
Assignee:
Associated Universities, Inc. (Washington, DC)
Patent Number(s):
US 5443813
Application Number:
07/711,208
OSTI ID:
870039
Country of Publication:
United States
Language:
English

References (2)

Synthesis of inorganic nanophase materials in supramolecular protein cages journal February 1991
Radioactive gold cluster immunoconjugates: Potential agents for cancer therapy
  • Hainfeld, James F.; Foley, Candice J.; Srivastava, Suresh C.
  • International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology, Vol. 17, Issue 3 https://doi.org/10.1016/0883-2897(90)90054-5
journal January 1990

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/424/530/
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