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Method for immunodiagnostic detection of dioxins at low concentrations

Patent ·
OSTI ID:869959
 [1];  [2];  [2];  [3];  [4]
  1. Danville, CA
  2. Livermore, CA
  3. Hochheim am Main, DE
  4. Eppstein/Ts., DE
+ Show Author Affiliations
A method is described for the use of monoclonal antibodies in a sensitive immunoassay for halogenated dioxins and dibenzofurans in industrial samples which contain impurities. Appropriate sample preparation and selective enzyme amplification of the immunoassay sensitivity permits detection of dioxin contaminants in industrial or environmental samples at concentrations in the range of a few parts per trillion.
Research Organization:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA
DOE Contract Number:
W-7405-ENG-48
Assignee:
Regents of University of California (Oakland, CA)
Patent Number(s):
US 5429925
OSTI ID:
869959
Country of Publication:
United States
Language:
English

References (6)

Improvement and application of an immunoassay for screening environmental samples for dioxin contamination journal November 1988
Antibody-Antigen and Antibody-Hapten Reactions book January 2018
ES&T Critical Review: Environmental monitoring by immunoassay journal March 1988
Monoclonal antibodies to chlorinated dibenzo-p-dioxins journal February 1986
The use of avidin-biotin interaction in immunoenzymatic techniques. journal August 1979
Analysis of polychlorinated dioxins and furans journal March 1984

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Related Subjects

/435/436/
amplification
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dioxin
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monoclonal
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permits
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trillion