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U.S. Department of Energy
Office of Scientific and Technical Information

Radiohalogenated half-antibodies and maleimide intermediate therefor

Patent ·
OSTI ID:867713

N-(m-radiohalophenyl) maleimide can be conjugated with a reduced antibody having a mercapto group to provide a radiolabelled half-antibody having immunological specific binding characteristics of whole antibody.

Research Organization:
Massachusetts Institute of Technology (Cambridge, MA)
DOE Contract Number:
FG02-86ER60460
Assignee:
President and Fellows of Harvard College (Cambridge, MA)
Patent Number(s):
US 4994557
OSTI ID:
867713
Country of Publication:
United States
Language:
English