Porphyrins for boron neutron capture therapy

Patent · Mon Jan 01 00:00:00 EST 1990

OSTI ID:867537

Miura, Michiko ^[1]; Gabel, Detlef ^[2]

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1. Center Moriches, NY
2. Bremen, DE

Novel compounds for treatment of brain tumors in Boron Neutron Capture Therapy are disclosed. A method for preparing the compounds as well as pharmaceutical compositions containing said compounds are also disclosed. The compounds are water soluble, non-toxic and non-labile boronated porphyrins which show significant uptake and retention in tumors.

• Research Organization: Associated Universities, Inc., Upton, NY (United States)
• DOE Contract Number: AC02-76CH00016
• Assignee: United States of America as represented by United States (Washington, DC)
• Patent Number(s): US 4959356
• OSTI ID: 867537
• Country of Publication: United States
• Language: English

Related Subjects

porphyrins
boron
neutron
capture
therapy
novel
compounds
treatment
brain
tumors
disclosed
method
preparing
pharmaceutical
compositions
containing
water
soluble
non-toxic
non-labile
boronated
significant
uptake
retention
pharmaceutical compositions
water soluble
neutron capture
boron neutron
capture therapy
compositions containing
novel compounds
pharmaceutical composition
compositions contain
novel compound
brain tumors
boronated porphyrins
/424/999/