Aminopropyl thiophene compounds

Patent · Mon Jan 01 00:00:00 EST 1990

OSTI ID:867325

Goodman, Mark M ^[1]

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1. Knoxville, TN

Radiopharmaceuticals useful in brain imaging comprising radiohalogenated thienylethylamine derivatives. The compounds are 5-halo-thiophene-2-isopropyl amines able to cross the blood-brain barrier and be retained for a sufficient length of time to allow the evaluation of regional blood flow by radioimaging of the brain.

• Research Organization: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
• Assignee: United States of America as represented by United States (Washington, DC)
• Patent Number(s): US 4914215
• OSTI ID: 867325
• Country of Publication: United States
• Language: English

Related Subjects

aminopropyl
thiophene
compounds
radiopharmaceuticals
useful
brain
imaging
comprising
radiohalogenated
thienylethylamine
derivatives
5-halo-thiophene-2-isopropyl
amines
blood-brain
barrier
retained
sufficient
length
time
allow
evaluation
regional
blood
flow
radioimaging
blood flow
sufficient length
radiohalogenated thienylethylamine
thienylethylamine derivatives
radiopharmaceuticals useful
comprising radiohalogenated
imaging comprising
brain imaging
blood-brain barrier
/999/