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Radioiodinated maleimides and use as agents for radiolabeling antibodies

Patent ·
OSTI ID:866558
 [1]
  1. Oak Ridge, TN
+ Show Author Affiliations

A radiopharmaceutical for antibody labeling comprising an iodophenyl maleimide that attaches thiol sites of proteins thereby maintaining bioreactivity largely located at the nitrogen sites.

Research Organization:
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN
Assignee:
United States of America as represented by United States (Washington, DC)
Patent Number(s):
US 4735792
OSTI ID:
866558
Country of Publication:
United States
Language:
English

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Related Subjects

/424/999/
agents
antibodies
antibody
antibody labeling
attaches
bioreactivity
comprising
iodophenyl
labeling
located
maintaining
maleimide
maleimides
nitrogen
nitrogen sites
proteins
radioiodinated
radiolabeling
radiolabeling antibodies
radiopharmaceutical
sites
thiol