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Title: Affinity labelling enzymes with esters of aromatic sulfonic acids

Abstract

Novel esters of aromatic sulfonic acids are disclosed. The specific esters are nitrophenyl p- and m-amidinophenylmethanesulfonate. Also disclosed is a method for specific inactivation of the enzyme, thrombin, employing nitrophenyl p-amidinophenylmethanesulfonate.

Inventors:
 [1];  [2]
  1. Riverhead, NY
  2. Shoreham, NY
Publication Date:
Research Org.:
Brookhaven National Laboratory (BNL), Upton, NY
OSTI Identifier:
862736
Patent Number(s):
US 4001087
Assignee:
United States of America (Washington, DC)
DOE Contract Number:  
AT(30-1)-16
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
affinity; labelling; enzymes; esters; aromatic; sulfonic; acids; novel; disclosed; specific; nitrophenyl; p-; m-amidinophenylmethanesulfonate; method; inactivation; enzyme; thrombin; employing; p-amidinophenylmethanesulfonate; sulfonic acid; sulfonic acids; affinity label; aromatic sulfonic; /435/999/

Citation Formats

Wong, Show-Chu, and Shaw, Elliott. Affinity labelling enzymes with esters of aromatic sulfonic acids. United States: N. p., 1977. Web.
Wong, Show-Chu, & Shaw, Elliott. Affinity labelling enzymes with esters of aromatic sulfonic acids. United States.
Wong, Show-Chu, and Shaw, Elliott. Sat . "Affinity labelling enzymes with esters of aromatic sulfonic acids". United States. https://www.osti.gov/servlets/purl/862736.
@article{osti_862736,
title = {Affinity labelling enzymes with esters of aromatic sulfonic acids},
author = {Wong, Show-Chu and Shaw, Elliott},
abstractNote = {Novel esters of aromatic sulfonic acids are disclosed. The specific esters are nitrophenyl p- and m-amidinophenylmethanesulfonate. Also disclosed is a method for specific inactivation of the enzyme, thrombin, employing nitrophenyl p-amidinophenylmethanesulfonate.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1977},
month = {1}
}

Patent:

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