A prominent large high-density lipoprotein at birth enriched in apolipoprotein C-I identifies a new group of infancts of lower birth weight and younger gestational age

Journal Article · Wed Oct 01 04:00:00 EDT 2003

OSTI ID:842566

Kwiterovich, Jr, Peter O ^[1]; Cockrill, Steven L; Virgil, Donna G; Garrett, Elizabeth; Otvos, James; Knight-Gibson, Carolyn; Alaupovic, Petar; Forte, Trudy; Farwig, Zachlyn N; Macfarlane, Ronald D

---

1. LBNL Library

Because low birth weight is associated with adverse cardiovascular risk and death in adults, lipoprotein heterogeneity at birth was studied. A prominent, large high-density lipoprotein (HDL) subclass enriched in apolipoprotein C-I (apoC-I) was found in 19 percent of infants, who had significantly lower birth weights and younger gestational ages and distinctly different lipoprotein profiles than infants with undetectable, possible or probable amounts of apoC-I-enriched HDL. An elevated amount of an apoC-I-enriched HDL identifies a new group of low birth weight infants.

• Research Organization: Ernest Orlando Lawrence Berkeley National Laboratory, Berkeley, CA (US)
• Sponsoring Organization: USDOE; National Institutes of Health Grants M01-RR-00052 and HL 18574 and HL 54566; Thomas Wilson Foundation
• DOE Contract Number: AC03-76SF00098
• OSTI ID: 842566
• Report Number(s): LBNL--54586
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
ADULTS
APOLIPOPROTEINS
DEATH
LIPOPROTEINS
Lipoprotein subclasses apolipoproteins triglycerides gestational age birth weight