Functional self-assembling bolaamphiphilic polydiacetylenes as colorimetric sensor scaffolds
Conjugated polymers capable of responding to external stimuli by changes in optical, electrical or electrochemical properties can be used for the construction of direct sensing devices. Polydiacetylene-based systems are attractive for sensing applications due to their colorimetric response to changes in the local environment. Here we present the design, preparation and characterization of self-assembling functional bolaamphiphilic polydiacetylenes (BPDAs) inspired by Nature's strategy for membrane stabilization. We show that by placing polar headgroups on both ends of the diacetylene lipids in a transmembranic fashion, and altering the chemical nature of the polar surface residues, the conjugated polymers can be engineered to display a range of radiation-, thermal- and pH-induced colorimetric responses. We observed dramatic nanoscopic morphological transformations accompanying charge-induced chromatic transitions, suggesting that both side chain disordering and main chain rearrangement play important roles in altering the effective conjugation lengths of the poly(ene-yne). These results establish the foundation for further development of BPDA-based colorimetric sensors.
- Research Organization:
- Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
- Sponsoring Organization:
- USDOE Director. Office of Science. Office of Basic Energy Sciences, Laboratory Directed Research and Development Program (US)
- DOE Contract Number:
- AC03-76SF00098
- OSTI ID:
- 841311
- Report Number(s):
- LBNL-53889; R&D Project: 519055; TRN: US200513%%608
- Journal Information:
- Journal of the American Chemical Society, Vol. 126, Issue 27; Other Information: Submitted to Journal of the American Chemical Society: Volume 126, No.27; Journal Publication Date: 07/14/2004; PBD: 28 May 2004
- Country of Publication:
- United States
- Language:
- English
Similar Records
Direct colorimetric detection of a receptor-ligand interaction by a polymerized bilayer assembly
New polydiacetylenes with visible chromophoric side groups