Selective molecular recognition, C-H bond activation, and catalysis in nanoscale reaction vessels
- LBNL Library
Supramolecular chemistry represents a way to mimic enzyme reactivity by using specially designed container molecules. We have shown that a chiral self-assembled M{sub 4}L{sub 6} supramolecular tetrahedron can encapsulate a variety of cationic guests, with varying degrees of stereoselectivity. Reactive iridium guests can be encapsulated and the C-H bond activation of aldehydes occurs, with the host cavity controlling the ability of substrates to interact with the metal center based upon size and shape. In addition, the host container can act as a catalyst by itself. By restricting reaction space and preorganizing the substrates into reactive conformations, it accelerates the sigmatropic rearrangement of enammonium cations.
- Research Organization:
- Ernest Orlando Lawrence Berkeley National Laboratory, Berkeley, CA (US)
- Sponsoring Organization:
- USDOE Director. Office of Science. Office of Basic Energy Sciences. Chemical Science Geosciences and Biosciences Division (US)
- DOE Contract Number:
- AC03-76SF00098
- OSTI ID:
- 840989
- Report Number(s):
- LBNL--56853
- Journal Information:
- Accounts of Chemical Research, Journal Name: Accounts of Chemical Research Journal Issue: 4 Vol. 38
- Country of Publication:
- United States
- Language:
- English
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