NMR studies of isotopically labeled RNA
Conference
·
OSTI ID:83382
- Univ. of Colorado, Boulder, CO (United States)
In summary, the ability to generate NMR quantities of {sup 15}N and {sup 13}C-labeled RNAs has led to the development of heteronuclear multi-dimensional NMR techniques for simplifying the resonance assignment and structure determination of RNAs. These methods for synthesizing isotopically labeled RNAs are only several years old, and thus there are still relatively few applications of heteronuclear multi-dimensional NMR techniques to RNA. However, given the critical role that RNAs play in cellular function, one can expect to see an increasing number of NMR structural studies of biologically active RNAs.
- Research Organization:
- Los Alamos National Lab., NM (United States)
- OSTI ID:
- 83382
- Report Number(s):
- LA--12893-C; CONF-9403228--; ON: DE95012795
- Country of Publication:
- United States
- Language:
- English
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