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Influence of polychlorinated biphenyls on the growth of chicken embryos

Journal Article · · Journal of Toxicology and Environmental Health
;  [1]
  1. Chub Women`s College, Gifu-ken (Japan)
Incubation of chicken embryos with either 0.01 or 0.03 ppm polychlorinated biphenyls (PCBs) for 12, 15, or 18 d resulted in a significant decrease in liver and body weight associated with enhanced mortality. Teratological examination revealed an increased frequency of malformations including hydrops, eventration, wry neck, and brevicollis. PCB exposure was also found to produce histologic damage to liver and cutaneous tissue. Our data demonstrate that exposure of chicks to PCBs during development results in a retardation of growth, an increased incidence of malformations, and histopathologic damage. 9 refs., 2 figs., 4 tabs.
Sponsoring Organization:
USDOE
OSTI ID:
79418
Journal Information:
Journal of Toxicology and Environmental Health, Journal Name: Journal of Toxicology and Environmental Health Journal Issue: 3 Vol. 42; ISSN 0098-4108; ISSN JTEHD6
Country of Publication:
United States
Language:
English