Enhanced Detection of Proteins in Microchip Separations by On-Chip Preconcentration
Conference
·
OSTI ID:788571
- ORNL
Microfluidic chips incorporating a semiporous glass filter were used to electrokinetically concentrate proteins on-chip prior to injection and electrophoretic analysis. Signal enhancements of >100-fold could be achieved for the microchip analysis of both native and SDS-denatured proteins using this technique.
- Research Organization:
- Oak Ridge National Lab., TN (US)
- Sponsoring Organization:
- US Department of Energy (US)
- DOE Contract Number:
- AC05-00OR22725
- OSTI ID:
- 788571
- Report Number(s):
- P01-110929
- Country of Publication:
- United States
- Language:
- English
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