Optimization Treatment Planning for Interstitial Brachytherapy Using the Adjoint Transport Method
Conference
·
OSTI ID:785345
Permanent radioactive seed implantation (interstitial brachytherapy) is becoming the preferred method of treating prostate cancers. The main goal of the treatment is to deliver a conformal dose to the tumor while simultaneously minimizing the dose to the normal tissue and sensitive tissue structures. The treatment plan determines the number of seeds, their embedded positions, and the dose delivered to the tissue by photons emitted from the seeds. This study adopts the adjoint method to calculate dose and mixed integer programming (MIP) to optimize the dose to regions of interest for the permanent implantation of {sup 125}I radioactive source seeds for prostate cancers.
- Research Organization:
- University of Wisconsin, Madison, WI (US)
- Sponsoring Organization:
- US Department of Energy (US)
- OSTI ID:
- 785345
- Report Number(s):
- NONE; ISSN 0003-018X; CODEN TANSAO; ISSN 0003-018X; CODEN TANSAO
- Country of Publication:
- United States
- Language:
- English
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