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Fast DNA analysis by laser mass spectrometry for human genome analysis

Journal Article · · AIP Conference Proceedings
DOI:https://doi.org/10.1063/1.47557· OSTI ID:76384
; ;  [1];  [2];  [1]
  1. Health Sciences Research Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6378 (United States)
  2. Cooperative Ward-Laboratory, Chinese Academia Sinica, Taipei (Taiwan)
Fast DNA sequencing by laser mass spectrometry is possible if the following 3 criteria are met: (1) Size of DNA fragment should be greater than 300 nucleotides. (2) Enough sensitivity to detect DNA produce from polymerases chain reactins (PCR). (3) Higher resolution of mass spectr. So far, the firt 2 criteria are met: If the resolution can be significantly improve, fast DNA sequencing by laser mass spectrometry weil be a reality in the near feature. (AIP)
Research Organization:
Oak Ridge National Laboratory
DOE Contract Number:
AC05-84OR21400
OSTI ID:
76384
Report Number(s):
CONF-940706--
Journal Information:
AIP Conference Proceedings, Journal Name: AIP Conference Proceedings Journal Issue: 1 Vol. 329; ISSN APCPCS; ISSN 0094-243X
Country of Publication:
United States
Language:
English

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