Applications of neutron radiography to histopathology. [Bone pathology and surgical histopathology]

Conference · Thu Jan 01 04:00:00 EST 1976 · Am. Soc. Test. Mater., Spec. Tech. Publ.; (United States)

OSTI ID:7360110

Boyne, P J ^[1]; Whittemore, W L

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1. Univ. of Texas Health Science Center, San Antonio

This paper describes a four-year study of the applications of neutron radiography to histopathology using an approach directed toward improvement in histologic sectioning, staining and tissue preparation techniques, and refinement in the application of neutron radiography in three areas: characterization of normal tissues of the facial bones and jaws; diagnosis of intraosseous tumors and a delineation of the invasion of the tumor into the surrounding bone; and the study of metallic semiburied implants attached to bone of the jaws. It was found to be possible, through the application of these techniques, to determine the presence of intraosseous tumor tissues and to determine the exact extension of the tumor tissue along the marrow vascular spaces and the neurovascular bundles of the bone. Additionally, it was found to be possible to delineate various normal anatomic structures of the facial bones and surrounding soft tissue, and to study the interface between semiburied metals and the surrounding bone and surrounding soft tissue. It is felt that neutron radiography will provide a significant diagnostic tool in research and in surgical pathology as an adjunct to the usual microscopic method of tissue examination, and additionally in the study of osseous-soft tissue interface with various types of metal implants. (auth)

• OSTI ID: 7360110
• Conference Information: Journal Name: Am. Soc. Test. Mater., Spec. Tech. Publ.; (United States) Journal Volume: 586
• Country of Publication: United States
• Language: English

Related Subjects

550600 -- Medicine
550900* -- Pathology
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
INDUSTRIAL RADIOGRAPHY
MATERIALS TESTING
MEDICAL SUPPLIES
NEUTRON RADIOGRAPHY
NONDESTRUCTIVE TESTING
PATIENTS
PERFORMANCE TESTING
PROSTHESES
SKELETAL DISEASES
SURGICAL MATERIALS
TESTING