Radiation-induced intracranial malignant fibrous histiocytoma
Journal Article
·
· Cancer; (United States)
DOI:https://doi.org/10.1002/1097-0142(197606)37:6<2960::AID-CNCR2820370653>3.0.CO;2-2·
OSTI ID:7349017
An autopsy case of radiation-induced intracranial malignant fibrous histiocytoma (fibroxanthosarcoma) is reported. The tumor developed in the region of the sella turcica 11 years after high dose radiotherapy of a chromophobe adenoma of the pituitary. The tumor had infiltrated the base of the brain as well as the base of the skull. Metastases were not found. The tumor was composed of an admixture of bizarre fibroblasts, histiocytes and giant cells, xanthoma cells and siderophages, with a storiform fibrous stroma. This appears to be the first documented instance of a malignant fibrous histiocytoma occurring intracranially after local x irradiation.
- Research Organization:
- Baltimore City Hospitals
- OSTI ID:
- 7349017
- Journal Information:
- Cancer; (United States), Journal Name: Cancer; (United States) Vol. 37:6; ISSN CANCA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADENOMAS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
DELAYED RADIATION EFFECTS
DISEASES
ELECTROMAGNETIC RADIATION
ENDOCRINE GLANDS
GLANDS
IONIZING RADIATIONS
IRRADIATION
LOCAL IRRADIATION
MEDICINE
NEOPLASMS
NERVOUS SYSTEM
NUCLEAR MEDICINE
ORGANS
PATIENTS
PITUITARY GLAND
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
SARCOMAS
SIDE EFFECTS
THERAPY
X RADIATION
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADENOMAS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
DELAYED RADIATION EFFECTS
DISEASES
ELECTROMAGNETIC RADIATION
ENDOCRINE GLANDS
GLANDS
IONIZING RADIATIONS
IRRADIATION
LOCAL IRRADIATION
MEDICINE
NEOPLASMS
NERVOUS SYSTEM
NUCLEAR MEDICINE
ORGANS
PATIENTS
PITUITARY GLAND
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
SARCOMAS
SIDE EFFECTS
THERAPY
X RADIATION