Dose-rate effects of Co60 irradiation on performance and physiology in monkeys. Topical report
One thousand rad /sup 60/Co was administered to 12 monkeys at 75 rad/min and to 8 monkeys at 50 rad/min while they performed a delayed match-to-sample, shock avoidance task. Only four at 75 rad/min and two at 50 rad/min showed early performance decrement and/or early transient incapacitation (PD-ETI), in contrast to 13 of 16 previously studied monkeys who showed PD-ETI with an average dose rate of 180 rad/min. A dose-rate effect was concluded. When these three groups were compared with an untrained group exposed to a 4000-rad gamma-neutron pulse, all showed similar degrees of hypotension postirradiation. But the onset of hypotension was delayed and its rate of fall prolonged as dose rate decreased. Tentative interpretation was that radiation thresholds for the induction of PD-ETI exist for cumulative dose (+ or - 300 rad, midbody) and dose rate (+ or - 30 rad/min). (GRA)
- Research Organization:
- Lovelace Foundation for Medical Education and Research, Albuquerque, N.Mex. (USA)
- DOE Contract Number:
- DASA01-70-C-0059; DNA001-74-C-0098
- OSTI ID:
- 7346911
- Report Number(s):
- AD-A-017505
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
MACACUS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL STRESS
COBALT 60
GAMMA RADIATION
HYPOTENSION
MONKEYS
PARTIAL BODY IRRADIATION
PERFORMANCE
RADIATION DOSES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
COBALT ISOTOPES
DOSES
ELECTROMAGNETIC RADIATION
EXTERNAL IRRADIATION
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-ODD NUCLEI
PRIMATES
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
VERTEBRATES
YEARS LIVING RADIOISOTOPES
560152* - Radiation Effects on Animals- Animals