Recent lung imaging studies. [Effectiveness for diagnosis of chronic obstructive pulmonary disease]

Conference · Thu Jan 01 00:00:00 EST 1976

OSTI ID:7332144

Taplin, G V; Chopra, S K

Radionuclide lung imaging procedures have been available for 11 years but only the perfusion examination has been used extensively and mainly for the diagnosis of pulmonary embolism (P.E.). Its ability to reveal localized ischemia makes it a valuable test of regional lung function as well as a useful diagnostic aid in P.E. Although it had been recognized for several years that chronic obstructive pulmonary disease (COPD) can cause lung perfusion defects which may simulate pulmonary embolism, relatively little use has been made of either the radioxenon or the radioaerosol inhalation lung imaging procedures until the last few years as a means of distinguishing P.E. from COPD. In this review emphasis is placed on our recent experience with both of these inhalation procedures in comparison with pulmonary function tests and roentgenography for the early detection of COPD in population studies. Equal emphasis is given to simultaneous aerosol ventilation-perfusion (V/P) imaging for a functional diagnosis of P.E. Two new developments in regional lung diffusion imaging, performed after the inhalation of radioactive gases and/or rapidly absorbed radioaerosols are described. The experimental basis for their potential clinical application in pulmonary embolism detection is presented.

• Research Organization: California Univ., Los Angeles (USA). Lab. of Nuclear Medicine and Radiation Biology
• DOE Contract Number: E(04-1)-GEN-12
• OSTI ID: 7332144
• Report Number(s): UCLA-12-1094; CONF-761060-5; IAEA-SM-210/313; TRN: 77-004968
• Resource Relation: Conference: IAEA symposium on medical radionuclide imaging, Los Angeles, CA, USA, 25 Oct 1976
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
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