Recent lung imaging studies. [Effectiveness for diagnosis of chronic obstructive pulmonary disease]
Radionuclide lung imaging procedures have been available for 11 years but only the perfusion examination has been used extensively and mainly for the diagnosis of pulmonary embolism (P.E.). Its ability to reveal localized ischemia makes it a valuable test of regional lung function as well as a useful diagnostic aid in P.E. Although it had been recognized for several years that chronic obstructive pulmonary disease (COPD) can cause lung perfusion defects which may simulate pulmonary embolism, relatively little use has been made of either the radioxenon or the radioaerosol inhalation lung imaging procedures until the last few years as a means of distinguishing P.E. from COPD. In this review emphasis is placed on our recent experience with both of these inhalation procedures in comparison with pulmonary function tests and roentgenography for the early detection of COPD in population studies. Equal emphasis is given to simultaneous aerosol ventilation-perfusion (V/P) imaging for a functional diagnosis of P.E. Two new developments in regional lung diffusion imaging, performed after the inhalation of radioactive gases and/or rapidly absorbed radioaerosols are described. The experimental basis for their potential clinical application in pulmonary embolism detection is presented.
- Research Organization:
- California Univ., Los Angeles (USA). Lab. of Nuclear Medicine and Radiation Biology
- OSTI ID:
- 7332144
- Report Number(s):
- UCLA-12-1094; CONF-761060-5; IAEA-SM-210/313
- Country of Publication:
- United States
- Language:
- English
Similar Records
Diagnosis of pulmonary embolism in patients with chronic obstructive pulmonary disease
Radioaerosol lung imaging in chronic obstructive pulmonary disease. Comparison with pulmonary function tests and roentgenography. [/sup 113m/In, /sup 99m/Tc, /sup 133/Xe tracer techniques]
Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISEASES
EMBOLI
IMAGES
LUNGS
MEDICINE
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
RADIONUCLIDE ADMINISTRATION
RESPIRATORY SYSTEM
RESPIRATORY SYSTEM DISEASES
SCINTISCANNING
VASCULAR DISEASES