Lipid and lipoprotein measurements in a normal adult American population

Journal Article · Tue Dec 31 23:00:00 EST 1974 · Lipids; (United States)

DOI:https://doi.org/10.1007/BF02532316· OSTI ID:7302956

Lindgren, F T ^[1]; Adamson, G L; Jenson, L C; Wood, P D

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1. Univ. of California, Berkeley

From a parent population of 774, a subpopulation of 160 normal adults ages 27 to 66 was randomly selected, 20 from each decade and sex. A detailed comparison was made by analytic ultracentrifugation and complete agarose gel electrophoresis on serum and the 1.006 g/ml top and bottom preparative ultracentrifuge lipoprotein fractions. The latter was internally standardized by total lipid and plasma total cholesterol and triglyceride determinations giving normal reference lipoprotein values. The reading procedure allowed the identification and quantification of floating ..beta.. and sinking pre-..beta... In the subpopulation, there were two of the former and 13 of the latter. For large scale clinical application of such quantitative lipoprotein electrophoresis full automation of the microdensitometry and calculations will be required.

• OSTI ID: 7302956
• Journal Information: Lipids; (United States), Journal Name: Lipids; (United States) Vol. 10:12; ISSN LPDSA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102 -- Chemical & Spectral Procedures
550200* -- Biochemistry
59 BASIC BIOLOGICAL SCIENCES
AUTOMATION
BLOOD SERUM
CENTRIFUGATION
CHEMICAL ANALYSIS
CHOLESTEROL
DENSITOMETERS
ELECTROPHORESIS
ESTERS
HUMAN POPULATIONS
HYDROXY COMPOUNDS
LIPIDS
LIPOPROTEINS
MEASURING INSTRUMENTS
MEASURING METHODS
ORGANIC COMPOUNDS
PHOTOMETERS
POPULATIONS
PROTEINS
SEPARATION PROCESSES
STANDARDS
STEROIDS
STEROLS
TRIGLYCERIDES
ULTRACENTRIFUGATION