Biological effects of low level exposures to chemicals and radiation
Book
·
OSTI ID:7272704
- ed.
In May 1990 a group of scientists representing several federal agencies, the International Society of Regulatory Toxicology and Pharmacology, the private sector, and academia met to develop a strategy to encourage the study of the biological effects of low level exposures (BELLE) to chemical agents and radioactivity. A workshop was held in 1991 with seven invited speakers focusing on the toxicological implications of biological adaptations. The selection of topics and speakers was designed to consider critically the concept of hormesis, not only in a broad, conceptual manner, but also at the molecular and biochemical levels. These presentations offered a complementary perspective on the diverse range of molecular mechanisms that can become activated at low levels of toxicant exposure. In addition to chemical toxicology research, an overview of current research on Effects of low-dose radiation on the immune response' was presented as well as Cellular adaptation as an important response during chemical carcinogenesis'. The final presentation was devoted to biostatistical considerations when designing studies that address issues associated with the biological responses to low doses of chemicals and radiation, as well as issues in interpretation of the findings from such studies.
- OSTI ID:
- 7272704
- Country of Publication:
- United States
- Language:
- English
Similar Records
Division of Biological and Medical Research annual research summary, 1983
Environmental hormesis and its fundamental biological basis: Rewriting the history of toxicology
Advances in exposure and toxicity assessment of particulate matter: An overview of presentations at the 2009 Toxicology and Risk Assessment Conference
Technical Report
·
Wed Aug 01 00:00:00 EDT 1984
·
OSTI ID:6629352
Environmental hormesis and its fundamental biological basis: Rewriting the history of toxicology
Journal Article
·
Wed Aug 15 00:00:00 EDT 2018
· Environmental Research
·
OSTI ID:23105889
Advances in exposure and toxicity assessment of particulate matter: An overview of presentations at the 2009 Toxicology and Risk Assessment Conference
Journal Article
·
Fri Jul 15 00:00:00 EDT 2011
· Toxicology and Applied Pharmacology
·
OSTI ID:21587781
Related Subjects
550200 -- Biochemistry
560120 -- Radiation Effects on Biochemicals
Cells
& Tissue Culture
560151* -- Radiation Effects on Animals-- Man
560300 -- Chemicals Metabolism & Toxicology
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSTRACTS
BIOCHEMICAL REACTION KINETICS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
CARCINOGENESIS
DOCUMENT TYPES
DOSE RATES
DOSE-RESPONSE RELATIONSHIPS
HAZARDOUS MATERIALS
IRRADIATION
KINETICS
LEADING ABSTRACT
LOW DOSE IRRADIATION
MATERIALS
PATHOGENESIS
RADIATION EFFECTS
REACTION KINETICS
TOXIC MATERIALS
TOXICITY
560120 -- Radiation Effects on Biochemicals
Cells
& Tissue Culture
560151* -- Radiation Effects on Animals-- Man
560300 -- Chemicals Metabolism & Toxicology
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSTRACTS
BIOCHEMICAL REACTION KINETICS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
CARCINOGENESIS
DOCUMENT TYPES
DOSE RATES
DOSE-RESPONSE RELATIONSHIPS
HAZARDOUS MATERIALS
IRRADIATION
KINETICS
LEADING ABSTRACT
LOW DOSE IRRADIATION
MATERIALS
PATHOGENESIS
RADIATION EFFECTS
REACTION KINETICS
TOXIC MATERIALS
TOXICITY