Scintigraphic evaluation of lymphoma: a comparative study of /sup 67/Ga-citrate and /sup 111/In-bleomycin

Journal Article · Wed May 25 04:00:00 EDT 1977 · J. Biol. Chem.; (United States)

OSTI ID:7259882

Bekerman, C; Moran, E M; Hoffer, P B; Hendrix, R W; Gottschalk, A

Sequential whole-body scans with both /sup 67/Ga-citrate and /sup 111/In-bleomycin were performed for 14 patients undergoing staging for Hodgkin's disease or other lymphomas. A comparison of these scans gave a sensitivity in detecting the pathologically-proved tumor sites of 84 percent for /sup 67/Ga-citrate and only 56 percent for /sup 111/In-bleomycin. In 12 patients, the gallium scan demonstrated the lesions more clearly; in the others, the uptake of the two radionuclides was equal. In no case was a clinically diagnosed or histologically proved lesion identified by /sup 111/In-bleomycin that was not also demonstrated by /sup 67/Ga-citrate. /sup 111/In-bleomycin does not complement the /sup 67/Ga-citrate scan in the scintigraphic evaluation of lymphomas.

• Research Organization: Univ. of Chicago
• OSTI ID: 7259882
• Journal Information: J. Biol. Chem.; (United States), Journal Name: J. Biol. Chem.; (United States) Vol. 252:10; ISSN JBCHA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ANTIBIOTICS
ANTIMITOTIC DRUGS
BETA DECAY RADIOISOTOPES
BLEOMYCIN
COMPARATIVE EVALUATIONS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
GALLIUM 67
GALLIUM ISOTOPES
HODGKINS DISEASE
INDIUM 111
INDIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LYMPHOMAS
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING