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Tunneling in proton transfer reactions in solution. Final report

Technical Report ·
OSTI ID:7259599
The rates of base-catalyzed ionization of several ketones have been measured. The results for 2,4-dimethyl-3-pentanone and 3,5-dimethyl-4-heptanone indicate that tunneling does not occur and the rate the determining step in detritiation is not the T/sup +/ transfer. In the reactions with acetylfurans, acetylthiophenes and acetylpyridines isotope effects vary in accordance with the current theory. Tunneling is significant only for the proton transfer from 2,4,6-trimethyl-3-acetylpyridine. In the iodination of acetone catalyzed by pyridine bases, k/sup H//k/sup D/ varies according to the current theory. Tunneling is significant only when sterically hindered pyridines are used. The rates of detritiation have been measured for several substituted acetophenones and isobutyrophenone.
Research Organization:
Lincoln Univ., Pa. (USA)
OSTI ID:
7259599
Report Number(s):
COO-3313-1
Country of Publication:
United States
Language:
English