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Characterization of an Acholeplasma laidlawii variant with a REP/sup -/ phenotype. [UV radiation]

Journal Article · · J. Bacteriol.; (United States)
OSTI ID:7256500
An Acholeplasma laidlawii variant has been isolated that has a REP/sup -/ phenotype. The properties of this variant, relative to parental cells, are: it exhibits no change in cell growth kinetics; it does not propagate single-stranded deoxyribonucleic acid (DNA) mycoplasmaviruses but does propagate double- stranded DNA mycoplasmaviruses; it converts parental circular single-stranded mycoplasmavirus DNA to double-stranded replicative forms that are not replicated further; it exhibits no change in host modification and restriction; and it has an increased ultraviolet light sensitivity. The REP/sup -/ isolate is the first stable mycoplasma variant to which a physiological defect has been attributed.
Research Organization:
Univ. of Rochester, NY
OSTI ID:
7256500
Journal Information:
J. Bacteriol.; (United States), Journal Name: J. Bacteriol.; (United States) Vol. 127:2; ISSN JOBAA
Country of Publication:
United States
Language:
English