Immediate effects of 33 to 180 rad/min (60)Co exposure on performance and blood pressure in monkeys. Topical report
Four groups of monkeys received 1000 rads (60)Co at 33, 50, 75, or 180 rad/min wholebody irradiation while performing a delayed matching-to-sample task. Systematic dose rate effects were observed on performance and blood pressure within the initial 20 min postirradiation. The incidence and severity of performance decrement (PD) increased with higher dose rate. The appearance of postirradiation hypotension was systematically delayed and its rate of fall prolonged as dose rate was lower. The hypotension likewise appeared less deep with lower dose rate exposure. Based on the calculated cumulative dose absorbed at the time of symptom appearance two coactive thresholds were proposed to exist: a total dose threshold of approximately 300 rads (midbody measurement), and a dose rate threshold of about 25 rad/min.
- Research Organization:
- Lovelace Foundation for Medical Education and Research, Albuquerque, NM (USA)
- DOE Contract Number:
- DNA001-74-C-0098
- OSTI ID:
- 7256470
- Report Number(s):
- AD-A-038470
- Resource Relation:
- Other Information: See also Rept. no. DNA--3660T dated 30 Jul 75, AD-A--017505
- Country of Publication:
- United States
- Language:
- English
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COMPARATIVE EVALUATIONS
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WHOLE-BODY IRRADIATION
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INTERMEDIATE MASS NUCLEI
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MINUTES LIVING RADIOISOTOPES
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560152* - Radiation Effects on Animals- Animals