Assays for myasthenia gravis
Patent
·
OSTI ID:7255349
This patent describes an improvement in a process for diagnosing myasthenia gravis. The process comprises the steps of preparing a complex of acetycholine receptor protein, toxin and a radioactive isotope, incubating the complex with a serum sample from a patient so as to join antibodies engendered in connection with myasthenia gravis to the complex, precipitating the complex joined with antibody with anti-immunoglobulin and measuring radioactivity, from the radioactive isotope, of the precipitated complex. The improvement is that the acetylcholine receptor protein is derived from cells of the TE671 Line.
- Assignee:
- Salk Institute for Biological Studies, San Diego, CA
- Patent Number(s):
- US 4789640
- OSTI ID:
- 7255349
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ANTIBODIES
ANTIGENS
BIOASSAY
BODY
CHEMICAL PREPARATION
DIAGNOSTIC TECHNIQUES
DISEASES
IMMUNOASSAY
IMMUNOLOGY
ISOTOPE APPLICATIONS
ISOTOPES
MATERIALS
MEDICINE
MUSCLES
NUCLEAR MEDICINE
ORGANIC COMPOUNDS
PROTEINS
RADIOASSAY
RADIOIMMUNOASSAY
RADIOIMMUNODETECTION
RADIOIMMUNOLOGY
RADIOISOTOPES
SYNTHESIS
TISSUES
TOXIC MATERIALS
TOXINS
TRACER TECHNIQUES
62 RADIOLOGY AND NUCLEAR MEDICINE
ANTIBODIES
ANTIGENS
BIOASSAY
BODY
CHEMICAL PREPARATION
DIAGNOSTIC TECHNIQUES
DISEASES
IMMUNOASSAY
IMMUNOLOGY
ISOTOPE APPLICATIONS
ISOTOPES
MATERIALS
MEDICINE
MUSCLES
NUCLEAR MEDICINE
ORGANIC COMPOUNDS
PROTEINS
RADIOASSAY
RADIOIMMUNOASSAY
RADIOIMMUNODETECTION
RADIOIMMUNOLOGY
RADIOISOTOPES
SYNTHESIS
TISSUES
TOXIC MATERIALS
TOXINS
TRACER TECHNIQUES