Caloric requirement of the critically ill septic patient

Journal Article · Fri Apr 01 04:00:00 EST 1988 · Crit. Care Med.; (United States)

DOI:https://doi.org/10.1097/00003246-198804000-00002· OSTI ID:7252726

Shizgal, H M; Martin, M F

The caloric requirement of the critically ill septic patient was determined by measuring body composition, by multiple isotope dilution, before and at 2-wk intervals while receiving total parenteral nutrition (TPN) in 86 septic and 57 nonseptic malnourished patients. All patients received a TPN solution containing 25% dextrose and 2.75% crystalline amino acids. The body composition of the nonseptic patients, who received 51.9 +/- 1.5 kcal/kg.day, improved significantly, while that of the septic patients, receiving 46.8 +/- 1.1 kcal/kg.day was only maintained. The relationship between caloric intake and the restoration of a malnourished body cell mass (BCM) was determined for each group by correlating, using multiple linear regression, the mean daily change in the BCM with the caloric intake and the nutritional state, as determined by body composition. According to the resultant regressions, an intake of 35.1 and 50.7 kcal/kg.day was required to maintain the BCM of the septic and nonseptic patients, respectively. To restore a depleted BCM, caloric intakes in excess of this amount are required.

• Research Organization: McGill Univ., Montreal, Quebec (Canada)
• OSTI ID: 7252726
• Journal Information: Crit. Care Med.; (United States), Journal Name: Crit. Care Med.; (United States) Vol. 16:4; ISSN CCMDC
• Country of Publication: United States
• Language: English

Related Subjects

550901* -- Pathology-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
BACTERIAL DISEASES
BODY COMPOSITION
CALORIFIC VALUE
COMBUSTION PROPERTIES
DISEASES
INFECTIOUS DISEASES
ISOTOPE APPLICATIONS
ISOTOPE DILUTION
MATHEMATICS
NUTRITION
PATHOGENESIS
PATIENTS
REGRESSION ANALYSIS
SEPTICEMIA
STATISTICS
TRACER TECHNIQUES