Malignant pleural mesothelioma due to environmental mineral fiber exposure in Turkey. Analysis of 135 cases

Journal Article · Tue Sep 01 04:00:00 EDT 1992 · Chest; (United States)

DOI:https://doi.org/10.1378/chest.102.3.790· OSTI ID:7249525

Selcuk, Z T; Coeplue, L Em; Emri, S; Kalyoncu, A F; Sahin, A A; Baris, Y I ^[1]

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1. Department of Chest Diseases, Hacettepe University School of Medicine, Ankara (Turkey)

We reviewed data from 135 patients with environment-associated malignant pleural mesothelioma (MPM) from the Central Anatolian region of Turkey. The most significant factors suggesting the diagnosis of MPM were the village where the patient resided and the typical presenting symptoms and signs of unilateral exudative pleural effusion associated with nonpleuritic chest pain. Computed tomography and ultrasonography were very useful for evaluating the extension of the tumor in the thoracic and abdominal cavities and chest wall. The tissue diagnosis was established by either thoracoscopy (39 percent) or pleural biopsy (39 percent) in the majority of the cases. The median survival after diagnosis was 13.52 months for erionite-associated MPM and 21.56 months for asbestos-associated MPM. The actuarial survival curves for the fibrous minerals were significantly different for survival computed both from onset of the symptoms and after diagnosis. Medical or surgical treatment or both did not change the outcome of the disease.

• OSTI ID: 7249525
• Journal Information: Chest; (United States), Journal Name: Chest; (United States) Vol. 102:3; ISSN CHETB; ISSN 0012-3692
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
ASBESTOS
ASIA
CARCINOGENESIS
DEVELOPING COUNTRIES
DISEASES
ENVIRONMENTAL EXPOSURE
MAMMALS
MAN
MEMBRANES
MIDDLE EAST
NEOPLASMS
PATHOGENESIS
PATIENTS
PLEURA
PRIMATES
SEROUS MEMBRANES
SURVIVAL CURVES
TURKEY
VERTEBRATES