Californium-252 sources for afterloading
Californium-252 neutron sources have been developed to investigate the value of this radionuclide in cancer therapy. The primary objective of the neutron source development is to meet the changing needs of the radiotherapist with safe, reliable, and uniform products. Thus far point and line sources containing 0.5 microgram to 1.0 milligram of californium-252 have been designed. The neutron source forms that are now available are reviewed, and the techniques by which they are fabricated are discussed. Many new combinations and configurations of californium-252 neutron sources are possible, if needed by the medical evaluators of this radioisotope. Californium-252 neutron sources are loaned by the United States Energy Research and Development Administration (ERDA) for medical research. Californium-252 sources are also loaned by ERDA for clinical investigations under a protocol of the Radiation Therapy Oncology Group, U.S. National Cancer Institute.
- Research Organization:
- Du Pont de Nemours (E.I.) and Co., Aiken, SC (USA). Savannah River Lab.
- DOE Contract Number:
- E(07-2)-1
- OSTI ID:
- 7231482
- Report Number(s):
- DP-MS-76-30; CONF-760436-7
- Country of Publication:
- United States
- Language:
- English
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Production, Distribution, and Applications of Californium-252 Neutron Sources
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62 RADIOLOGY AND NUCLEAR MEDICINE
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ALPHA DECAY RADIOISOTOPES
CALIFORNIUM 252
CALIFORNIUM ISOTOPES
DISEASES
EVEN-EVEN NUCLEI
FABRICATION
HEAVY NUCLEI
ISOTOPES
MEDICINE
NEOPLASMS
NEUTRON SOURCES
NUCLEAR MEDICINE
NUCLEI
PARTICLE SOURCES
QUALITY ASSURANCE
RADIATION SOURCES
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
THERAPY
USES
YEARS LIVING RADIOISOTOPES