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Multi-dentate ligand complexes of lanthanide and actinide metal ions

Thesis/Dissertation ·
OSTI ID:7222254
The coordinate chemistry of several multidentate ligands has been studied to evaluate their potential as actinide(IV) chelating agents and to understand the effect of tetracatecholate ligands on Am(III) distribution in vivo. Lanthanides were used as models of actinides in the same oxidation state and with similar ionic radii. The aqueous and bioinorganic chemistry of Pu(IV) and Am(III) is reviewed, and the rationale behind the design and evaluation of new chelating agents is discussed. The synthesis and isolation of bic-, tris-, and tetrakis(catecholato) lanthanide(III) complexes formed in basic (pH > 11) aqueous solutions and x-ray crystal structures of the tris- and tetrakis(catecholato) gadolinium(III) compounds are reported. The stability and protonation behavior of Ce(III) with catechol and hydroxypyridinone derivatives of desferrioxamine B (called DFOCAMC and DFOHOPO, respectively) as determined by potentiometric and spectral titrations and the electrochemistry of Ce-DFOCAMC are described. The formation constants and the stability of the complexes are reported. The synthesis of two different types of chelating polymers and the preliminary investigation of their metal chelating polymers and the preliminary investigation of their metal binding ability are presented. The first type is a polystyrene supported catechoyl amide and the second type incorporates the catechoyl moiety into the backbone of a linear polyamide.
Research Organization:
California Univ., Berkeley (USA)
OSTI ID:
7222254
Country of Publication:
United States
Language:
English