Radionuclide emission computed tomography of the head with /sup 99m/Tc and a scintillation camera

Journal Article · Fri Apr 01 00:00:00 EST 1977 · J. Nucl. Med.; (United States)

OSTI ID:7216558

Jaszczak, R J; Murphy, P H; Huard, D; Burdine, J A

To investigate the potential application of radionuclide computed tomography (RCT) to nuclear medicine imaging using /sup 99m/Tc, a tomographic system using a lightweight scintillation camera for brain imaging was constructed, and lesion contrast with RCT and conventional scintigraphy was compared. The detector revolves once around the patient's head at constant angular velocity, requiring approximately 20 min. Nine sections are reconstructed from the data, using either a Fourier transform or a filtered backprojection algorithm. In a phantom simulating the radionuclide distribution observed during brain imaging, quantitative lesion contrast was far superior in the RCT images. In a series of 25 patients with intracranial lesions, the average RCT lesion contrast was superior to that of standard scintigraphy by a factor of more than 2. An RCT image of an experimentally infarcted dog's heart, taken after the injection of /sup 99m/Tc-MAA into the left atrium, also showed excellent correspondence to the gross anatomic defect. Although problems of photon absorption may occur in imaging larger body areas, RCT imaging in this feasibility study produced surprisingly good results that warrant further investigation of the technique.

• Research Organization: Baylor Coll. of Medicine, Houston, TX
• OSTI ID: 7216558
• Journal Information: J. Nucl. Med.; (United States), Vol. 18:4
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BRAIN
SCINTISCANNING
TOMOGRAPHY
TECHNETIUM 99
COMPARATIVE EVALUATIONS
ISOMERIC NUCLEI
PATIENTS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CENTRAL NERVOUS SYSTEM
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NERVOUS SYSTEM
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics