Postirradiation carcinoma of the thyroid gland

Journal Article · Thu Jul 01 04:00:00 EDT 1976 · J. Miss. State Med. Assoc.; (United States)

OSTI ID:7216538

Martin, G H

In the early 1920's many infants and children received x-ray therapy for such conditions as enlarged thymus, hypertrophy of the tonsils and adenoids, cervical adenitis, sinusitis, and so forth. Unfortunately, the thyroid gland frequently received direct or scattered irradiation during these treatments. As the irradiated population has grown older it has become apparent that these people have an increased incidence of thyroid cancer. Recent publicity on this problem in the newspaper, radio, and television has alarmed individuals or their parents who in turn have consulted their physicians for advice. All individuals with a history of head and neck irradiation should be considered as having an increased risk of developing thyroid cancer. These patients should be examined every two years indefinitely. Fortunately, only a small percentage of irradiated individuals develop thyroid tumors. Most of the tumors found have been benign. Those which are malignant have been well differentiated, papillary, or follicular neoplasms which grow slowly, metastasize relatively late, and are curable by surgical removal before metastasis has occurred. If on palpation of the thyroid gland one or more firm, discrete nodules are palpated, these should be removed regardless of other findings. A scan may be useful in assessing the functional status of the nodule and may give some indication as to whether the nodule is malignant or benign. If the scan shows a cold area which corresponds with a palpable mass, the patient should be considered for prompt surgical exploration. If the scan shows a hot nodule, it is usually not malignant, but should be closely observed for change.

• OSTI ID: 7216538
• Journal Information: J. Miss. State Med. Assoc.; (United States), Journal Name: J. Miss. State Med. Assoc.; (United States) Vol. 17:7; ISSN MSMJB
• Country of Publication: United States
• Language: English

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560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
CARCINOMAS
CHILDREN
DELAYED RADIATION EFFECTS
DISEASES
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ORGANS
PATIENTS
PRIMATES
RADIATION EFFECTS
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
SURGERY
THERAPY
THYROID
VERTEBRATES