Respiratory disease mortality among uranium miners

Journal Article · Thu Jan 01 04:00:00 EST 1976 · Ann. N.Y. Acad. Sci.; (United States)

DOI:https://doi.org/10.1111/j.1749-6632.1976.tb23123.x· OSTI ID:7212815

Archer, V E; Gillam, J D; Wagoner, J K

A mortality analysis of a group of white and Indian uranium miners was done by a life-table method. A significant excess of respiratory cancer among both whites and Indians was found. Nonmalignant respiratory disease deaths among the whites are approaching cancer in importance as a cause of death, probably as a result of diffuse parenchymal radiation damage. Exposure-response curves for nonsmokers are linear for both respiratory cancer and ''other respiratory disease''. Cigaret smoking elevates and distorts that curve. Light cigaret smokers appear to be most vulnerable to lung parenchymal damage. The predominant histologic cancer among nonsmokers is small-cell undifferentiated, just as it is among cigaret smokers.

• Research Organization: National Inst. for Occupational Safety and Health, Salt Lake City
• OSTI ID: 7212815
• Journal Information: Ann. N.Y. Acad. Sci.; (United States), Journal Name: Ann. N.Y. Acad. Sci.; (United States) Vol. 271; ISSN ANYAA
• Country of Publication: United States
• Language: English

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