Morphometric, structural, and ultrastructural studies of tench (Tinca tinca L. ) hepatocytes after copper sulfate administration

Journal Article · Sat Feb 01 04:00:00 EST 1992 · Environmental Research; (United States)

DOI:https://doi.org/10.1016/S0013-9351(05)80018-0· OSTI ID:7206342

Roncero, V; Duran, E; Soler, F; Masot, J; Gomez, L ^[1]

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1. Faculty of Veterinary Science, Caceres (Spain)

A structural, ultrastructural, and morphometric study was made of the liver parenchyma of 12 adult tench (Tinca tinca, L.) subjected to acute experimental copper sulfate poisoning. The lesions observed were characterized by the accumulation in the cytoplasm of large amounts of hemoglobinemic pigment produced by intense hemolysis, initially in Kuppfer cells and by the last stage of the experiment in hepatocytes. This process became increasingly severe, and culminated in the massive necrosis of large areas of liver parenchyma, which led to the death of tench 12 days after the start of the experiment.

• OSTI ID: 7206342
• Journal Information: Environmental Research; (United States), Journal Name: Environmental Research; (United States) Vol. 57:1; ISSN ENVRA; ISSN 0013-9351
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
AQUATIC ORGANISMS
CELL CONSTITUENTS
COPPER
CYTOPLASM
ELEMENTS
FISHES
LIVER CELLS
METALS
MORPHOLOGICAL CHANGES
SENSITIVITY
SOMATIC CELLS
TOXICITY
TRANSITION ELEMENTS
ULTRASTRUCTURAL CHANGES
VERTEBRATES