Influence of mobile phase alcohol modifiers on HPLC of polycyclic aromatics using bonded phase cyclodextrin columns

Journal Article · Thu Dec 31 23:00:00 EST 1987 · Anal. Lett.; (United States)

DOI:https://doi.org/10.1080/00032718808070863· OSTI ID:7201678

Tarr, M A; Nelson, G; Patonay, G; Warner, I M

Recent studies have shown that formation constants for cyclodextrin inclusion complexes are increased in the presence of certain alcohols. This paper describes a preliminary investigation of the effects of mobile phase alcohol modifiers on HPLC separation of polynuclear aromatics using cyclodextrin bonded phases. Dramatic changes in the chromatography are reported in the presence of alcohol. Some discussion is provided as to how these results may be used to increase the selectivity of HPLC separations using cyclodextrin bonded phases.

• Research Organization: Emory Univ., Atlanta, GA (USA)
• OSTI ID: 7201678
• Journal Information: Anal. Lett.; (United States), Journal Name: Anal. Lett.; (United States) Vol. 21:5; ISSN ANALB
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400105* -- Separation Procedures
ALCOHOLS
AROMATICS
CHROMATOGRAPHY
DATA
EFFICIENCY
EXPERIMENTAL DATA
HYDROCARBONS
HYDROXY COMPOUNDS
INFORMATION
LIQUID COLUMN CHROMATOGRAPHY
NUMERICAL DATA
ORGANIC COMPOUNDS
PHASE STUDIES
POLYCYCLIC AROMATIC HYDROCARBONS
SEPARATION PROCESSES