Reactions of carbonyl compounds with Grignard reagents in the presence of cerium chloride

Journal Article · Wed Jun 07 00:00:00 EDT 1989 · Journal of the American Chemical Society; (USA)

DOI:https://doi.org/10.1021/ja00194a037· OSTI ID:7197318

Imamoto, Tsuneo; Takiyama, Nobuyuki; Nakamura, Kimikazu; Hatajima, Toshihiko; Kamiya, Yasuo ^[1]

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1. Chiba Univ. (Japan)

The addition of Grignard reagents to ketones is significantly enhanced by cerium chloride with remarkable suppression of side reactions, particularly enolization. Some esters, which are prone to side reactions, also react readily with Grignard reagents in the presence of cerium chloride to give normal reaction products in reasonable to high yields.

• OSTI ID: 7197318
• Journal Information: Journal of the American Chemical Society; (USA), Journal Name: Journal of the American Chemical Society; (USA) Vol. 111:12; ISSN 0002-7863; ISSN JACSA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400000* -- Chemistry
400201 -- Chemical & Physicochemical Properties
ALCOHOLS
ALKALINE EARTH METAL COMPOUNDS
CARBONYLS
CERIUM CHLORIDES
CERIUM COMPOUNDS
CHEMICAL REACTIONS
CHLORIDES
CHLORINE COMPOUNDS
DATA
EXPERIMENTAL DATA
GRIGNARD REAGENTS
HALIDES
HALOGEN COMPOUNDS
HYDROXY COMPOUNDS
INFORMATION
MAGNESIUM COMPOUNDS
MEASURING INSTRUMENTS
MEASURING METHODS
NUMERICAL DATA
ORGANIC COMPOUNDS
ORGANOMETALLIC COMPOUNDS
RARE EARTH COMPOUNDS