Serum 2,3,7,8-tetrachlorodibenzo-p-dioxin levels in Air Force health study participants - preliminary report

Journal Article · Fri Jun 24 04:00:00 EDT 1988 · JAMA, J. Am. Med. Assoc.; (United States)

OSTI ID:7161005

In 1978, the US Air Force responded to a congressional mandate to initiate an epidemiologic study of the possible health effects of exposure to herbicides and their 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) contaminants in Air Force veterans who served in the Ranch Hand defoliation operation during the Vietnam conflict. Accordingly, the Air Force conducted a nonconcurrent prospective study, the Air Force Health Study, of all 1267 members of the Ranch Hand unit and a series of matched controls. This phase of the Air Force study focused on measuring serum TCDD levels in 150 Ranch Hand veterans and 50 controls. All participants were enlisted men; the Ranch Hand veterans had been either herbicide loaders or herbicide specialists in Vietnam. The demographic and health characteristics of Ranch Hand personnel and controls were similar; however, their serum TCDD levels differed markedly.

• OSTI ID: 7161005
• Journal Information: JAMA, J. Am. Med. Assoc.; (United States), Journal Name: JAMA, J. Am. Med. Assoc.; (United States) Vol. 259:24; ISSN JAMAA
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADIPOSE TISSUE
ANIMAL TISSUES
ASIA
BODY
CHEMICAL ANALYSIS
CHRONIC EXPOSURE
CONNECTIVE TISSUE
DEVELOPING COUNTRIES
DIOXIN
HETEROCYCLIC COMPOUNDS
MILITARY PERSONNEL
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
PERSONNEL
QUANTITATIVE CHEMICAL ANALYSIS
TISSUES
VIET NAM