Enzymatic repair of DNA: sites of hydrolysis by the Escherichia coli endonuclease specific for pyrimidine dimers (Correndonuclease II). [UV radiation]

Journal Article · Tue Sep 07 00:00:00 EDT 1976 · Biochemistry; (United States)

OSTI ID:7145008

Braun, A G ^[1]; Radman, M; Grossman, L

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1. Brandeis Univ., Waltham, MA

The Escherichia coli uvrA, uvrB endonuclease (correndonuclease II) incises ultraviolet irradiated DNA at a phosphodiester bond 5' to a pyrimidine dimer on the damaged DNA strand. As a result of its action a 3'-hydroxyl and 5'-phosphoryl terminus is generated.

• OSTI ID: 7145008
• Journal Information: Biochemistry; (United States), Journal Name: Biochemistry; (United States) Vol. 15:18; ISSN BICHA
• Country of Publication: United States
• Language: English

Related Subjects

560111 -- Radiation Effects on Biochemicals-- In Vitro-- (-1987)
560131* -- Radiation Effects on Microorganisms-- Basic Studies-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AZINES
BACTERIA
BIOCHEMICAL REACTION KINETICS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BIOLOGICAL REPAIR
CHEMICAL REACTIONS
DECOMPOSITION
DIMERS
DNA
ELECTROMAGNETIC RADIATION
ENZYMES
ESCHERICHIA COLI
HETEROCYCLIC COMPOUNDS
HYDROLYSIS
KINETICS
LYSIS
MICROORGANISMS
NUCLEASES
NUCLEIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PHOSPHOTRANSFERASES
PYRIMIDINES
RADIATION EFFECTS
RADIATIONS
REACTION KINETICS
RECOVERY
REPAIR
SOLVOLYSIS
TRANSFERASES
ULTRAVIOLET RADIATION