Packed column supercritical fluid chromatography using deactivated stationary phases

Journal Article · Mon Aug 01 04:00:00 EDT 1988 · Anal. Chem.; (United States)

DOI:https://doi.org/10.1021/ac00166a011· OSTI ID:7144057

Ashraf-Khorassani, M; Taylor, L T; Henry, R A

A new cross-linked cyanopropyl bonded phase silica (Delta-bond) has been studied as a stationary phase for packed column supercritical fluid chromatography of basic nitrogen-containing compounds. The bonded phase impedes access to uncapped silanol sites, thereby giving rise to better peak shapes and more rapid elution without the necessity of a polar modifier in the mobile phase. Experiments both at elevated temperature and in the presence of a methanol modifier revealed that there is no short- or long-term deleterious effect on the column as opposed to the conventional cyanopropyl phase.

• Research Organization: Virginia Polytechnic Institute and State Univ., Blacksburg (USA)
• DOE Contract Number: FG22-81PC40799
• OSTI ID: 7144057
• Journal Information: Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 60:15; ISSN ANCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400105* -- Separation Procedures
ADSORPTION
CHALCOGENIDES
CHROMATOGRAPHY
COLUMN PACKING
DATA
EXPERIMENTAL DATA
INFORMATION
MINERALS
NITROGEN COMPOUNDS
NUMERICAL DATA
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
OXIDE MINERALS
OXIDES
OXYGEN COMPOUNDS
PACKINGS
PHASE STUDIES
SEPARATION PROCESSES
SILICA
SILICON COMPOUNDS
SILICON OXIDES
SORPTION
SORPTIVE PROPERTIES
SUPERCRITICAL FLUID CHROMATOGRAPHY
SURFACE PROPERTIES