Theileria parva: effects of irradiation on a culture of parasitized bovine lymphoid cells. [Gamma radiation]

Journal Article · Wed Jan 01 00:00:00 EST 1975 · Exp. Parasitol.; (United States)

DOI:https://doi.org/10.1016/0014-4894(75)90038-7· OSTI ID:7139630

Irvin, A D; Brown, C G.D.; Stagg, D A

Aliquots of a culture of Theileria parva-infected bovine lymphoid cells were irradiated at 0, 300, 600, 900, and 1200 rads. The short-term effects of irradiation were evaluated on examination of Giemsa-stained smears and on autoradiography of cells labeled with (/sup 3/H)thymidine. Irradiation inhibited cell division but parasite division did not appear to be inhibited and macroschizont nuclear particles increased in number, frequently to several hundred per schizont. There was no evidence of an increased percentage switch from macro- to microschizont. Apparently viable cells were still present in all cultures 4 days after irradiation.

• Research Organization: East African Veterinary Research Organization, Muguga, Kenya
• OSTI ID: 7139630
• Journal Information: Exp. Parasitol.; (United States), Vol. 38:1
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CELL DIVISION
BIOLOGICAL RADIATION EFFECTS
LYMPHOCYTES
PROTOZOA
CELL CULTURES
DOSE-RESPONSE RELATIONSHIPS
GAMMA RADIATION
PARASITES
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CONNECTIVE TISSUE CELLS
ELECTROMAGNETIC RADIATION
INVERTEBRATES
IONIZING RADIATIONS
LEUKOCYTES
MICROORGANISMS
RADIATION EFFECTS
RADIATIONS
SOMATIC CELLS
560121* - Radiation Effects on Cells- External Source- (-1987)