Parametric imaging of experimentally simulated Wolff-Parkinson-White syndrome conduction abnormalities in dogs: a concise communication

Journal Article · Wed Jan 01 00:00:00 EST 1986 · Am. J. Physiol. Imag.; (United States)

OSTI ID:7125903

Weismueller, P H; Henze, E; Adam, W E; Roth, J; Bitter, F; Stauch, M

In order to test the diagnostic potential of phase analysis of radionuclide ventriculography (RNV) for localizing accessory bundles in Wolff-Parkinson-White (WPW) syndrome, 24 experimental runs were performed in three open chest instrumented dogs. After a baseline study, WPW syndrome was simulated by stimulation at seven different sites around the base of the ventricles, and RNV's were obtained. Subsequent data processing including Fourier transformation allowed the localization of the site of the first inward motion of the ventricles by an isophasic wave display. In sinus rhythm, the septum contracted first. During ectopic premature ventricular stimulation by triggering the atrial signal, the phase scan was altered only when the stimulus was applied earlier than 20 ms before the expected QRS complex during sinus rhythm. During stimulation with fixed frequency, only the left lateral positions of the premature stimulation were detected by phase analysis with a sensitivity of 86%. Neither the antero- or posteroseptal nor the right ventricular premature contraction pattern could be exactly localized.

• Research Organization: Univ. of Ulm (Germany, F.R.)
• OSTI ID: 7125903
• Journal Information: Am. J. Physiol. Imag.; (United States), Vol. 1:4
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CARDIOVASCULAR DISEASES
DIAGNOSIS
HEART
RADIOISOTOPE SCANNING
DOGS
FOURIER TRANSFORMATION
IMAGE PROCESSING
SIMULATION
TECHNETIUM ISOTOPES
ANIMALS
BODY
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DISEASES
INTEGRAL TRANSFORMATIONS
ISOTOPES
MAMMALS
ORGANS
PROCESSING
TRANSFORMATIONS
VERTEBRATES
550601* - Medicine- Unsealed Radionuclides in Diagnostics