Total body sodium and chlorine in normal adults

Journal Article · Tue Jun 01 04:00:00 EDT 1976 · Metab., Clin. Exp.; (United States)

DOI:https://doi.org/10.1016/0026-0495(76)90061-5· OSTI ID:7116402

Ellis, K J; Vaswani, A; Zanzi, I; Cohn, S H

Absolute levels of total body sodium (TBNa) and total body chlorine (TBCl) were determined in 81 normal adults (39 males, 42 females) by means of total body neutron activation analysis (TBNAA). The ages of the subjects ranged from 30 to 90 yr. The mean values for both TBNa and TBCl remained relatively constant throughout the age span studied for males, but decreased slightly for females over 60 yr of age. In order for the absolute masurements of Na and Cl to be of clinical value, the values muxt be compared to a predicted value based on the sex and body habitus of the individual. Normalization of TBNa values relative to body dimensions (weight, height, body surface area) were evaluated. In addition, TBNa was related to total body calcium (TBCa), which reflects skeletal mass, and TBK, which reflects muscle, or lean body mass. Normalization in terms of a linear combination of the TBCa and TBK was found to be the most satisfactory of all those studied. Sodium excess, Na/sub ES/, defined as the amount of body sodium (mEq) in excess of body chlorine (mEq) was determined. Sodium excess correlated well with total body calcium. Values for total body sodium and chlorine obtained in the present study were compared with values previously reported in the literature.

• Research Organization: Brookhaven National Lab., Upton, NY
• OSTI ID: 7116402
• Journal Information: Metab., Clin. Exp.; (United States), Journal Name: Metab., Clin. Exp.; (United States) Vol. 25:6; ISSN METAA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400101* -- Activation
Nuclear Reaction
Radiometric & Radiochemical Procedures
ACTIVATION ANALYSIS
ADULTS
ALKALI METALS
ANIMALS
BARYON REACTIONS
BODY
CHEMICAL ANALYSIS
CHLORINE
ELEMENTS
HADRON REACTIONS
HALOGENS
IN VIVO
MAMMALS
MAN
METALS
NEUTRON REACTIONS
NONMETALS
NUCLEAR REACTIONS
NUCLEON REACTIONS
PRIMATES
SODIUM
VERTEBRATES