delta-aminolevulinic acid dehydratase: inhibition in ducks dosed with lead shot

Journal Article · Fri Oct 01 04:00:00 EDT 1976 · Environ. Res.; (United States)

OSTI ID:7110073

Finley, M T; Dieter, M P; Locke, L N

Lead concentration in blood and erythrocyte delta-aminolevulinic acid dehydratase (ALAD) activity was measured in mallard ducks dosed with one all-lead shot or one lead--iron combination shot. For 2 weeks after dosage, lead in blood of ducks given an all-lead shot was fourfold higher than in those dosed with lead--iron shot. At 3 and 4 weeks, the differences in lead residues were directly proportional to lead content of the shots. ALAD activities measured at these intervals were inversely correlated (P less than 0.01) with the concentration of lead in the blood, suggesting that biochemical responses to the two types of shot were dependent upon the quantity of lead present.

• Research Organization: Fish and Wildlife Service, Laurel, MD
• OSTI ID: 7110073
• Journal Information: Environ. Res.; (United States), Journal Name: Environ. Res.; (United States) Vol. 12:2; ISSN ENVRA
• Country of Publication: United States
• Language: English

Related Subjects

550200 -- Biochemistry
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINO ACIDS
AMINOLEVULINIC ACID
ANIMALS
BIOCHEMICAL REACTION KINETICS
BIOLOGICAL MATERIALS
BIRDS
BLOOD
BLOOD CELLS
BODY FLUIDS
CARBOXYLIC ACIDS
CATALYSIS
DUCKS
ELEMENTS
ENZYME INHIBITORS
ENZYMES
ERYTHROCYTES
FOWL
IRON
KINETICS
LEAD
METABOLISM
METALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
QUANTITY RATIO
REACTION KINETICS
TRANSITION ELEMENTS
VERTEBRATES