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Effect of cigarette smoking on survival of patients with angiographically documented coronary artery disease: report from the CASS registry

Journal Article · · JAMA, J. Am. Med. Assoc.; (United States)
; ; ; ;
Through a multicenter registry of patients in the Coronary Artery Surgery Study, the author prospectively evaluated morbidity and mortality in 4165 smokers with angiographically proved coronary artery disease, 2675 of whom continued to smoke and 1490 of whom quit. At five years, mortality was 22% for those who continued smoking and 15% for quitters. The relative risk for mortality in continuers vs quitters was 1.55. The adverse effect of smoking mainly took the form of higher frequencies of myocardial infarction-associated death and sudden death: the frequencies of these events during follow-up in continuers vs quitters were 7.9% vs 4.4% for myocardial infarction-associated death and 2.8% vs 1.5% for sudden death. This study supports the recommendation that patients with coronary artery disease should stop smoking.
Research Organization:
Univ. of Washington, Seattle
OSTI ID:
7106989
Journal Information:
JAMA, J. Am. Med. Assoc.; (United States), Journal Name: JAMA, J. Am. Med. Assoc.; (United States) Vol. 255:8; ISSN JAMAA
Country of Publication:
United States
Language:
English

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Related Subjects

550602 -- Medicine-- External Radiation in Diagnostics-- (1980-)
560300* -- Chemicals Metabolism & Toxicology
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AEROSOLS
ARTERIES
BIOLOGICAL EFFECTS
BIOMEDICAL RADIOGRAPHY
BLOOD VESSELS
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COLLOIDS
CORONARIES
DIAGNOSTIC TECHNIQUES
DISEASES
DISPERSIONS
MEDICINE
MORTALITY
MYOCARDIAL INFARCTION
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIOLOGY
RESIDUES
SMOKES
SOLS
TOBACCO SMOKES
VASCULAR DISEASES