Use of carbonyl iron to induce iron loading in the mussel Mytilus edulis

Journal Article · Thu Feb 01 00:00:00 EST 1990 · Bulletin of Environmental Contamination and Toxicology; (USA)

DOI:https://doi.org/10.1007/BF01700137· OSTI ID:7098809

Bootsma, N; Macey, D J; Webb, J; Talbot, V ^[1]

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1. Murdoch Univ. (Australia)

It is now recognized that in organisms such as marine mussels, the prior presence of one metal can be important in determining the ultimate toxicological response to a second challenge by a different metal species. Thus, for example, the presence of iron in the mussel Mytilus edulis profoundly affects the subsequent accumulation of zinc. To determine these synergistic (or indeed antagonistic) effects in an organism such as the mussel, it is important to be able to both load the animal rapidly, and ensure that the metal ends up in a form which is ultimately the same as that found in the animal in the natural environment. Unfortunately, considerable problems have arisen with the form in which iron has been loaded into mussels. Recently, carbonyl iron has been used to induce iron loading in rats. This form of iron is prepared by reacting elemental iron at high temperatures with carbon monoxide to form iron pentacarbonyl. This study was thus undertaken to determine whether carbonyl iron could be used for the rapid non-toxic iron loading of the mussel Mytilus edulis. Such loading could subsequently be used for the investigation of synergistic metal accumulation in mussels, a topic of considerable interest due to their use as marine pollution indicator organisms. Biochemical aspects of this tissue iron loading, including the isolation and characterization of the major metal-binding protein ferritin, have been reported previously.

• OSTI ID: 7098809
• Journal Information: Bulletin of Environmental Contamination and Toxicology; (USA), Vol. 44:2; ISSN 0007-4861
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
IRON CARBONATES
UPTAKE
METALS
SYNERGISM
BIOLOGICAL EFFECTS
CARBONYLATION
GILLS
KIDNEYS
LIVER
MUSSELS
PANCREAS
TISSUE DISTRIBUTION
WATER POLLUTION
ANIMALS
AQUATIC ORGANISMS
BODY
CARBON COMPOUNDS
CARBONATES
CHEMICAL REACTIONS
DIGESTIVE SYSTEM
DISTRIBUTION
ELEMENTS
ENDOCRINE GLANDS
GLANDS
INVERTEBRATES
IRON COMPOUNDS
MOLLUSCS
ORGANS
OXYGEN COMPOUNDS
POLLUTION
RESPIRATORY SYSTEM
TRANSITION ELEMENT COMPOUNDS
560300* - Chemicals Metabolism & Toxicology