Implications of liver activity associated with /sup 133/Xe ventilation lung scans
Journal Article
·
· Clin. Nucl. Med.; (United States)
A series of 35 xenon-133 (/sup 133/Xe) ventilation studies yielded nine cases demonstrating accumulation of activity in the liver. Maximum intrahepatic deposition of radioxenon occurred during the washout phase of the study. In addition to those clinical instances which make this phenomenon possible, i.e., obesity, alcoholic-induced liver steatosis and diabetes mellitus, we found that hyperlipidemia and coronary artery disease also favor xenon-133 localization into the hepatic parenchyma. It is concluded that the lipid avidity of /sup 133/Xe facilitates its liver accumulation hyperlipidemic patients and in patients with coronary artery disease, and that this action may be explored to further understand deranged metabolic pathways in the liver of these patients. Hepatic accumulation of /sup 133/Xe during ventilation studies must be considered when assessing regional ventilation/perfusion relationships.
- Research Organization:
- Univ. of Minnesota, Minneapolis
- OSTI ID:
- 7097638
- Journal Information:
- Clin. Nucl. Med.; (United States), Journal Name: Clin. Nucl. Med.; (United States) Vol. 3:5; ISSN CNMED
- Country of Publication:
- United States
- Language:
- English
Similar Records
Xenon-133 retention in hepatic steatosis - correlation with liver biopsy in 45 patients: concise communication
Xenon-133 hepatic retention ratio: A useful index for fatty liver quantification
Postperfusion xenon-133 ventilation scintigraphy with a narrow window
Conference
·
Tue May 01 00:00:00 EDT 1979
· J. Nucl. Med.; (United States)
·
OSTI ID:6289985
Xenon-133 hepatic retention ratio: A useful index for fatty liver quantification
Journal Article
·
Sun Oct 01 00:00:00 EDT 1989
· Journal of Nuclear Medicine; (USA)
·
OSTI ID:5158925
Postperfusion xenon-133 ventilation scintigraphy with a narrow window
Conference
·
Sun Sep 01 00:00:00 EDT 1985
· AJR, Am. J. Roentgenol.; (United States)
·
OSTI ID:5179028
Related Subjects
550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
551001* -- Physiological Systems-- Tracer Techniques
560171 -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Man-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL LOCALIZATION
BODY
CARDIOVASCULAR DISEASES
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIABETES MELLITUS
DIGESTIVE SYSTEM
DISEASES
ENDOCRINE DISEASES
EVEN-ODD NUCLEI
GLANDS
INHALATION
INTAKE
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIPIDS
LIVER
LUNGS
METABOLIC DISEASES
METABOLISM
NUCLEI
ORGANIC COMPOUNDS
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIONUCLIDE KINETICS
RESPIRATORY SYSTEM
UPTAKE
XENON 133
XENON ISOTOPES
551001* -- Physiological Systems-- Tracer Techniques
560171 -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Man-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL LOCALIZATION
BODY
CARDIOVASCULAR DISEASES
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIABETES MELLITUS
DIGESTIVE SYSTEM
DISEASES
ENDOCRINE DISEASES
EVEN-ODD NUCLEI
GLANDS
INHALATION
INTAKE
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIPIDS
LIVER
LUNGS
METABOLIC DISEASES
METABOLISM
NUCLEI
ORGANIC COMPOUNDS
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIONUCLIDE KINETICS
RESPIRATORY SYSTEM
UPTAKE
XENON 133
XENON ISOTOPES