Right ventricular ejection fraction in patients with acute anterior and inferior myocardial infarction assessed by radionuclide angiography

Journal Article · Thu Jun 01 04:00:00 EDT 1978 · Circulation; (United States)

DOI:https://doi.org/10.1161/01.CIR.57.6.1078· OSTI ID:7091156

Tobinick, E; Schelbert, H R; Henning, H; LeWinter, M; Taylor, A; Ashburn, W L; Karliner, J S

We measured right and left ventricular ejection fraction (EF) from high frequency time-activity curves obtained during the initial passage of an intravenous bolus of /sup 99m/Tc (Sn) pyrophosphate. In 22 normal controls right ventricular EF averaged 0.52 +- 0.04 (SD). In 24 acute anterior or lateral infarction patients right ventricular EF was normal (0.56 +- 0.10), while left ventricular EF was reduced (0.45 +- 0.10, P < 0.001 vs controls). In 19 acute inferior infarction patients left ventricular EF also was depressed (0.51 +- 0.09, P < 0.001 vs controls). Among 7 of 19 inferior infarction patients with right ventricular infarction by scintigraphy, right ventricular EF was reduced (0.39 +- 0.05; P < 0.001 vs normals; P < 0.01 vs inferior infarction patients without right ventricular involvement). In the latter group right ventricular EF averaged 0.51 +- 0.10 (NS vs normals). We conclude (1) a single injection of /sup 99m/Tc (Sn) pyrophosphate can identify right and left ventricular dysfunction and infarct location in acute myocardial infarction, (2) right ventricular EF is well-preserved except when inferior infarction involves the right ventricle.

• Research Organization: Univ. of California, San Diego
• OSTI ID: 7091156
• Journal Information: Circulation; (United States), Journal Name: Circulation; (United States) Vol. 57:6; ISSN CIRCA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BODY
BODY FLUIDS
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COMPLEXES
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
HEART
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEASURING METHODS
MUSCLES
MYOCARDIAL INFARCTION
MYOCARDIUM
NUCLEI
ODD-EVEN NUCLEI
ORGANS
OXYGEN COMPOUNDS
PHOSPHORUS COMPOUNDS
PYROPHOSPHATES
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
TECHNETIUM 99
TECHNETIUM ISOTOPES
TIN COMPLEXES
YEARS LIVING RADIOISOTOPES