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A fully automated contour detection for gated radionuclide ventriculography with a slant hole collimator

Conference · · J. Nucl. Med.; (United States)
OSTI ID:7089908
A fully automated method has been developed to compute accurate and reproducible left ventricular (LV) ejection fraction (EF) and volume curve from gated pool images with a slant hole collimator. The procedure of the method is summarized as follows: 1.An optimal preprocessing filter is selected by phantom experiment so that signal to noise ratio becomes maximum. 2. The cosine and sine transform images are used for separating the ventricle from auricle and defining center of the LV. 3. Radial profiles are generated from the center of the LV and smoothed by forth order Fourier series (FS) approximation. 4. The points corresponding to the first crossing of a threshold along each profiles are identified as edge. Variable threshold, defined from the value on detected contour of a averaged image, is used on each profile. 5. LV countour is obtained by connecting all the edge points defined on radial profiles by FS. 6. The shape of sequentially detected contours is checked by displaying them in cine mode superimposed with original images. This new method has successfully detected LV contour in 91% of the 46 patients. The LVEF obtained by the method closely related to that of contrast ventriculography. (correlation coefficient (r)=.90). The end diastolic volume has also a good correlation to contrast ventriculography (r=.90). The present method is believed to be reliable and valuable for quantitative analysis of LV function using the slant hole collimator.
Research Organization:
Shimadzu Corp., Kyoto
OSTI ID:
7089908
Report Number(s):
CONF-840619-
Conference Information:
Journal Name: J. Nucl. Med.; (United States) Journal Volume: 25:5
Country of Publication:
United States
Language:
English